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Decoding communication between tumors and their environment to find better therapies

PI | CURRENT MEMBERS

PRINCIPAL INVESTIGATOR

Ikjot S. Sohal
Principal Investigator
Assistant Professor of Cancer Biology
Department of Biological Sciences
University of North Texas

I am a scientist dedicated to conducting fundamental and translational research that tackles the current and emerging challenges in cancer treatment. My dedication extends beyond the lab, as I am deeply committed to offering individualized mentorship, promoting inclusive teaching, and engaging in community outreach. My ultimate goal is to inspire and train the next generation of scientists, fostering a collaborative and inclusive environment that propels impactful fundamental and translational cancer research forward.

I have published >15 papers in peer-reviewed journals, received research grants from the Department of Defense and the Indiana Clinical & Translational Sciences Institute, and received Young Investigator Award for my work and Purdue Postdoc Mentor Award in recognition of my mentoring efforts. In my spare time, I enjoy playing squash and volunteering in my community.


CURRENT LAB MEMBERS

We are looking for passionate Ph.D. students. If interested, contact Dr. Sohal at ikjot.sohal@unt.edu.

Sudhanshu Shekhar, Ph.D.

Postdoctoral Research Associate
Functional genomics & Computational biology

Sudhanshu.Shekhar@unt.edu

About Me

I am a scientist committed to studying the regulation of gene expression and its impact on human disease phenotypes by integrating methods from statistical genetics, computational biology, and functional genomics. Before joining the Sohal Lab, I trained under Dr. Andrea Kasinski at Purdue University, delineating the functions of circular RNA in cancer progression, and completed my Ph.D. under Dr. Peristera Paschou, where my work focused on identifying genetically-regulated gene expression changes in Tourette syndrome and myasthenia gravis. I then acquired postdoctoral training at the Won Lab at UNC Chapel Hill, centered on functional genomics and using Massively Parallel Reporter Assays (MPRA) to study genetic variant-driven gene expression changes in neuronal diseases.

I am excited to join Dr. Sohal’s lab and bring my functional genomics background to uncover new mechanisms of tumor-microenvironment communication and advance personalized-therapy modalities. Alongside my research, I am passionate about mentoring and training future scientists. I look forward to supporting students in the lab as they develop their own research skills and interests.

Outside the lab, I enjoy playing cricket and pickleball.

Emmanuel Lamptey

Graduate student
Ph.D. candidate in Biochemistry & Molecular Biology

Emmanuel.Lamptey@unt.edu

About Me

I am an aspiring biomedical researcher with a strong interest in understanding cancer molecular mechanisms and translating these discoveries into therapies that improve patient outcomes. I have a BSc in Medical Laboratory Sciences and an MPhil in Molecular Biology, which have given me training in both clinical and basic research. My long-term goal is to bridge these areas by translating basic cancer biology into patient-centered therapeutic strategies.

I am excited to join Dr. Sohal’s lab because his work on exploring intrinsic and extrinsic regulators of cell-to-cell communication in cancer closely aligns with my research interests and the potential to uncover targetable pathways that can be leveraged for innovative cancer therapies. I am eager to contribute to and grow within such a rigorous and impactful research environment.

Outside the lab, I enjoy movies and anime, gaming, cooking, music, and engaging in intellectually stimulating conversations which continually fuel my curiosity and passion for scientific inquiry.

Tanvi Verma

Undergraduate student
B.A. in Biology with Minors in Chemistry and Psychology

Tanvi.Verma@unt.edu

About Me

I was born in Punjab, India, and ever since I was five years old, I’ve dreamt of becoming a doctor. That dream has shaped not only my academic path at UNT, but also the way I approach learning and teaching. I work as a Lead Tutor at the Learning Center and a Peer-Led Team Learning Leader for Human Anatomy and Physiology and these roles have allowed me to guide other students while strengthening my own understanding in the process.

I’m especially excited to join the Sohal Lab because it gives me the chance to explore research hands-on and see how the science I’ve studied in class will play out in the lab. For me, this is an important step toward combining my love of science with my long-term goal of practicing medicine. Beyond academics, I enjoy dancing, traveling, and spending time with my family.

Diya Patel

Undergraduate student
B.S. in Biology and Minors in Chemistry

DiyaPatel12@my.unt.edu

About Me

I am a pre-med student at the University of North Texas, pursuing a Bachelor’s degree in Biology with a minor in Chemistry. My academic interests center on oncology, with a strong passion for studying the mechanisms of cancer development, progression, and treatment. My long-term goal is to attend medical school and specialize in pediatric oncology, where I can combine research with compassionate care to improve outcomes for children and their families.

Outside of academics, I value spending time with my family, exploring new places, and listening to music, which provide balance and inspiration in my academic and professional journey.

Judi Awadi

Undergraduate student
B.S. in Biology and Minors in Chemistry

JudiAwadi@my.unt.edu

About Me

I am an aspiring forensic scientist currently pursuing a major in Biology with a concentration in Forensic Science at the University of North Texas, alongside a minor in Chemistry. My career interests lie in forensic science research, with a focus on forensic pathology. Through this research experience, I am developing hands-on skills in scientific analysis while also gaining exposure to research in tumor biology and cell-to-cell communication, which play important roles in understanding disease progression and treatment outcomes. This opportunity is helping build a strong foundation in analytical thinking and scientific research methods. 

Outside of academics I enjoy cooking and baking, photography, and running. These hobbies help me stay motivated as I pursue my academic goals. I am grateful for the opportunity to contribute to research and look forward to continuing to develop my skills as a scientist.

Sanjana Munagala

TAMS student
General Mathematics and Science Track

SanjanaMunagala2@my.unt.edu

About Me

I am an aspiring doctor and researcher who is currently studying at the Texas Academy of Mathematics and Science (TAMS) at UNT. Currently I have a strong interest in immunology, cancer biology, and translational medicine. My long-term goal is to become a physician who not only provides compassionate care to patients, but also contributes to research that advances our understanding of disease. And that’s why I am thrilled to be working at Sohal Lab where I am investigating how extracellular vesicles contribute to tumor-mediated T-cell suppression in lung cancer. Through this research, I am gaining hands-on laboratory experience while deepening my understanding of biological concepts and the scientific method.

Outside of the lab, I enjoy baking desserts, drawing and painting. These hobbies encourage creativity and curiosity, both of which I bring into my research. I am appreciative to have this opportunity to contribute to cancer research, and I am excited to be part of the discoveries that shape the future of medicine.